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Fresh Start

Opioids

Pharmaceutical opioids are a group of medicines that may be prescribed to treat pain. These medicines are very effective to treat pain when prescribed and used correctly, but they are highly addictive and must always be used under close supervision of a doctor. Illicit opioids are a group of illegal substances under the classification of a depressant because opioids slow down the brain and the central nervous system. They have similar effects to pharmaceutical opioids, but are unregulated, often vary in strength, they may be contaminated with other dangerous substances and are therefore unpredictable in their effects.

How common are opioid substance use disorders in Australia for all people aged 14+?

Highest to lowest substance use in Australia for 14+ years old:

  1. Alcohol 77%
  2. Cannabis 11.6%
  3. Nicotine/Cigarettes 11%
  4. Misused Prescription Opioids 3.3%
  5. Benzodiazepines 1.6%
  6. Methamphetamines 1.3%
  7. Psychoactive Substances 0.2%
  8. Illicit Opioids 0.1%

Opioids are ranked 4th and 8th in relation to all substance use disorders and substance misuse.

Opioid antagonist are substances that block the opioid receptors in the nervous system. These can help reverse the effects of an opioid overdose and can be used to treat substance use disorders.

Opioids, including heroin, methadone, opium, morphine and codeine, work by binding to the opioid receptors in the brain. Opioid antagonists block and replace opioid substances from the nervous system receptors, thereby stopping and reversing the effects of the opioids, including the sensations of being “high” and cravings.

Short-term effects Long-term effects
  • Memory problems
  • Extreme sedation
  • Dulled senses
  • Vomiting, nausea, dizziness & shallow, laboured breathing
  • Seizures/tremors
  • Mood swings
  • Addiction
  • Constipation
  • Insomnia
  • Skin infections
  • Nasal infections
  • Lung infections
  • Drug tolerance
  • HIV/AIDS
  • Hepatitis C
  • Stroke
  • Heart attack, endocarditis (heart infection)
  • Kidney damage

Opioid use can result in a range of different social and health-related harms.

Opioid poisoning can be caused when people:

  • take more medication than was prescribed
  • combine opioids with other drugs and substances such as alcohol and other sedatives
  • have a change in their health status or there is a decrease in their tolerance.

Three signs of opioid poising include loss of consciousness, respiratory depression and pinpoint pupils. Poisoning can result in hospitalisation and death.

Social harms of opioid use may include injuries and death related to violence to or by someone using opioids, driving under the influence, bloodborne viral infections such as HIV and hepatitis C and antisocial behaviour. The opioid burden of disease in 2011 was a total of 0.9% of the total in Australia. These account for accidental poisoning at 63%, and opioid dependence at 30%. A further 7.8% of the burden was attributed to suicide and self-inflicted injuries.

Opioid dependence is recognised by changes in behavioural, cognitive and physical wellbeing. This includes:

  • strong cravings for opioids and difficulty in controlling and limiting their use
  • continuing use despite current and potential harms and consequences caused by opioid use
  • increased tolerance to the substance
  • physical withdrawal symptoms when use stops
  • prioritising use of opioids over people and other obligations such as engaging with friends and family or going to work or school

At Fresh Start we offer a supported rapid detoxification through pharmacotherapy. We utilize opioid antagonists and supporting pharmaceuticals to decrease and manage withdrawal symptoms when opioid use ceases. We encourage patients to stop using 3 to 4 days prior to medical detoxification to further minimise the impacts of withdrawal symptoms.

The Fresh Start Clinic team work together to minimise and decrease the effects of withdrawal symptoms. They will also discuss support needs including access to appropriate living arrangements, and medical and other professional support during this period.

Recovery from substance use disorders is possible through careful medical management, counselling support and the appropriate addiction treatment.

Opioid harm in Australia: and comparisons between Australia and Canada (Full publication;[24 Oct 2018]edition) (AIHW)